Best Acne Treatment. Initiation Routines to Minimize Irritation

• Less frequent (every 2-3 night) application may be useful
early in therapy; begin with low concentration [2.5%]; avoid
more irritating formulations (e.g. acetone- & alcohol- based
gels) unless skin is oily.
• Alternatively, apply for 15 minutes the 1
st
 evening.  Each
evening the time should be doubled until left on for 4 hours
& subsequently all night.  Once tolerance is achieved, the
strength may be increased to 5%.  
• Alternatively, BP can be applied for 2 hours for 4 nights, 4
hours for 4 nights, and then left on all night.