Best Acne Treatment. Isotretinoin (Accutane, Clarus) Highlights

• Official indications: severe nodular and/or inflammatory acne,
acne conglobata & recalcitrant acne.
• Other considerations:
♦ extensive acne involving face and trunk, associated with scarring;
failure to respond to or inability to tolerate systemic antibiotics
and/or hormonal therapy; family history
♦ Significant psychological distress because of acne
• Due to common side effects, avoid concurrent acne topicals, vitamin
A supplements, and follow-up topical retinoids for about 4 months